Hans D Ochs Selected Research

Wiskott-Aldrich Syndrome

1/2022	Diagnosis and clinical management of Wiskott-Aldrich syndrome: current and emerging techniques.
1/2021	Hematopoietic Stem Cell Therapy for Wiskott-Aldrich Syndrome: Improved Outcome and Quality of Life.
1/2020	Excellent outcomes following hematopoietic cell transplantation for Wiskott-Aldrich syndrome: a PIDTC report.
1/2020	Multiplexed Proteomic Analysis for Diagnosis and Screening of Five Primary Immunodeficiency Disorders From Dried Blood Spots.
1/2018	R-loops cause genomic instability in T helper lymphocytes from patients with Wiskott-Aldrich syndrome.
8/2011	Long-term outcome and lineage-specific chimerism in 194 patients with Wiskott-Aldrich syndrome treated by hematopoietic cell transplantation in the period 1980-2009: an international collaborative study.
4/2010	X-linked thrombocytopenia (XLT) due to WAS mutations: clinical characteristics, long-term outcome, and treatment options.
1/2009	Mutations of the Wiskott-Aldrich Syndrome Protein affect protein expression and dictate the clinical phenotypes.
1/2009	Wiskott-Aldrich syndrome: diagnosis, clinical and laboratory manifestations, and treatment.
8/2008	Restricted immunoglobulin constant heavy G chain genes in primary immunodeficiencies.

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Hans D Ochs Research Topics

Disease

27	Infections 01/2022 - 01/2002
22	Primary Immunodeficiency Diseases 01/2022 - 01/2002
17	Wiskott-Aldrich Syndrome 01/2022 - 12/2003
9	Type 1 Hyper-IgM Immunodeficiency Syndrome 01/2019 - 04/2002
9	Thrombocytopenia 1 01/2018 - 10/2003
8	Bruton type agammaglobulinemia 01/2022 - 04/2002
7	X-Linked Syndrome Enteropathy Polyendocrinopathy Immune Dysregulation 06/2020 - 08/2005
6	Neutropenia 01/2022 - 01/2008
6	Job Syndrome (Hyper-IgE Syndrome) 01/2019 - 07/2008
5	Autoimmune Diseases (Autoimmune Disease) 01/2022 - 01/2008
5	Thrombocytopenia (Thrombopenia) 06/2020 - 03/2002
5	Common Variable Immunodeficiency 01/2019 - 08/2008
5	Hemophilia A (Haemophilia) 11/2009 - 07/2004
4	Agammaglobulinemia (Hypogammaglobulinemia) 01/2022 - 07/2006
4	Neoplasms (Cancer) 01/2022 - 04/2003
4	Inflammation (Inflammations) 01/2022 - 10/2016
4	Severe combined immunodeficiency due to adenosine deaminase deficiency 01/2020 - 05/2002
4	Atopic Dermatitis (Atopic Eczema) 01/2019 - 11/2006
4	Reinfection 01/2016 - 11/2003
3	COVID-19 01/2022 - 01/2021
3	Measles 01/2022 - 12/2011
3	Bacterial Infections (Bacterial Infection) 06/2018 - 02/2010
3	Communicable Diseases (Infectious Diseases) 04/2014 - 12/2009
3	Pneumonia (Pneumonitis) 04/2012 - 01/2002
3	Tetanus 12/2011 - 11/2003
3	Hyper-IgM Immunodeficiency Syndrome (Hyper-IgM Syndrome) 09/2010 - 04/2002
3	Severe Combined Immunodeficiency (Bare Lymphocyte Syndrome) 12/2009 - 04/2003
2	Chronic Granulomatous Disease 01/2022 - 01/2020
2	Virus Diseases (Viral Diseases) 01/2022 - 02/2011
2	Autoimmune Hemolytic Anemia (Cold Agglutinin Disease) 06/2020 - 12/2005
2	Food Hypersensitivity (Food Allergy) 06/2020 - 05/2007
2	Eczema 06/2020 - 09/2010
2	Leukemia 01/2020 - 09/2015
2	Cicatrix (Scar) 01/2019 - 04/2005
2	Ataxia Telangiectasia (Louis Bar Syndrome) 01/2019 - 08/2008
2	Rubella (German Measles) 01/2019 - 12/2011
2	Eosinophilia 05/2018 - 05/2007
2	Graft vs Host Disease (Graft-Versus-Host Disease) 04/2017 - 04/2014
2	Sepsis (Septicemia) 01/2015 - 07/2006
2	Hepatitis 12/2011 - 07/2006
2	Disease Susceptibility (Diathesis) 09/2010 - 09/2009
2	Psoriasis (Pustulosis Palmaris et Plantaris) 11/2008 - 11/2003
1	Cytokine Release Syndrome 01/2022
1	Multiple Myeloma 01/2022
1	Hemorrhage 01/2022
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022
1	Lymphopenia (Lymphocytopenia) 01/2022
1	Genetic Predisposition to Disease (Genetic Predisposition) 01/2021
1	Zika Virus Infection 01/2021

Drug/Important Bio-Agent (IBA)

15	Proteins (Proteins, Gene)FDA Link 01/2022 - 03/2002
14	Immunoglobulin G (IgG)IBA 01/2022 - 03/2003
13	CD40 Ligand (CD40L)IBA 01/2019 - 04/2002
12	Immunoglobulins (Immunoglobulin)IBA 01/2020 - 01/2002
11	Intravenous Immunoglobulins (IVIG)FDA Link 10/2018 - 01/2002
9	AntibodiesIBA 01/2022 - 04/2002
7	Agammaglobulinaemia Tyrosine KinaseIBA 01/2022 - 04/2002
7	Immunoglobulin M (IgM)IBA 01/2019 - 03/2003
6	Wiskott-Aldrich Syndrome ProteinIBA 01/2018 - 01/2004
5	Immunoglobulin E (IgE)IBA 01/2019 - 11/2006
5	DNA (Deoxyribonucleic Acid)IBA 09/2010 - 04/2003
5	Factor VIII (Coagulation Factor VIII)IBA 11/2009 - 07/2004
4	VaccinesIBA 01/2019 - 01/2002
4	STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA 02/2012 - 07/2008
3	AutoantibodiesIBA 01/2022 - 12/2018
3	Cytidine DeaminaseIBA 01/2019 - 11/2003
3	Tetanus Toxoid (Vaccine, Tetanus)FDA Link 06/2018 - 11/2003
3	Immunoglobulin A (IgA)IBA 03/2005 - 11/2003
2	G-Protein-Coupled Receptors (Receptors, G Protein Coupled)IBA 01/2022 - 12/2018
2	CytokinesIBA 01/2022 - 11/2006
2	Transcription Factors (Transcription Factor)IBA 01/2021 - 06/2020
2	Peptides (Polypeptides)IBA 01/2020 - 11/2007
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2019 - 01/2016
2	Adenosine DeaminaseIBA 01/2019 - 02/2009
2	AntigensIBA 12/2011 - 10/2004
2	LigandsIBA 02/2009 - 09/2008
2	I-kappa B KinaseIBA 03/2005 - 11/2003
2	Uracil-DNA GlycosidaseIBA 03/2005 - 10/2003
2	NF-kappa B (NF-kB)IBA 10/2004 - 11/2003
1	Blood Proteins (Serum Proteins)IBA 01/2022
1	Immunologic Factors (Immunomodulators)IBA 01/2022
1	B-Cell Maturation AntigenIBA 01/2022
1	Chimeric Antigen ReceptorsIBA 01/2022
1	EpitopesIBA 01/2022
1	ChemokinesIBA 01/2022
1	Amyloid Precursor Protein Secretases (beta-Secretase)IBA 01/2022
1	Oxidoreductases (Dehydrogenase)IBA 01/2022
1	tocilizumab (atlizumab)FDA Link 01/2022
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2022
1	Interleukin-10 (Interleukin 10)IBA 01/2022
1	bis(3- bis(4- chlorophenyl)methyl- 4- dimethylaminophenyl)amineIBA 01/2022
1	NADP (NADPH)IBA 01/2022
1	Immunomodulating AgentsIBA 01/2022
1	Virus ReceptorsIBA 01/2021

Therapy/Procedure

21	Therapeutics 01/2022 - 01/2002
6	Hematopoietic Stem Cell Transplantation 01/2022 - 07/2005
6	Cell Transplantation 01/2020 - 11/2010
3	Transplantation 04/2017 - 12/2009
2	Bone Marrow Transplantation (Transplantation, Bone Marrow) 10/2016 - 04/2003
2	Splenectomy 01/2015 - 04/2010
1	Drug Therapy (Chemotherapy) 01/2022